The information on this website is for educational purposes only. Do not act or rely upon the information on this website without seeking independent professional medical advice.  Prolotherapy is a medical technique. As with any medical technique, results will vary among individuals, and there is no guarantee that you will receive the same outcome as patient reports here. Prolotherapy injections may not work for you and as with all medical procedures there are risks involved. These risks should be discussed with a qualified health care professional prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

Joint and Musculoskeletal Pain


Advances in Regenerative Medicine: High - Density Platelet Rich Plasma and Stem Cell Prolotherapy for Musculoskeletal Pain.  (2011)
This article summarizes how Biocellular Prolotherapy works to resolve musculoskeletal pain. 

Evidence-Based Use of Dextrose Prolotherapy for Musculoskeletal Pain. (2011)
This scientific literature review shows there is good evidence to support the use of dextrose prolotherapy for various types of musculoskeletal pain involving the spine, pelvis and peripheral joints.

Journal of Prolotherapy International Medical Editorial Board Consensus Statement on the Use of Prolotherapy for Musculoskeletal Pain. (2011)
This paper explains the theory, scientific evidence, methods, and applications for the procedure of prolotherapy in the treatment of musculoskeletal pain. 

Prolotherapy: a clinical review of its role in treating chronic musculoskeletal pain. (2011)
This article talks about how prolotherapy remains a promising option for the treatment of painful musculoskeletal conditions, particularly when other standard treatments have proved ineffective.

Prolotherapy in Primary Care.  (2010)
This review article summarizes the medical evidence supporting the use of Prolotherapy in primary care. 

The New Age of Prolotherapy.  (2010)
Discusses the advances that have been made in Prolotherapy including Platelet Rich Plasma, adult stem cell sources such as bone marrow and adipose, and the use of imaging with musculoskeletal ultrasound to increase precision in diganosis and treatment. 

Prolotherapy.  (2008)
This chapter from Complementary and Integrative Medicine in Pain Management (Springer Publications) details the science behind Prolotherapy and how it works to resolve musculoskeletal and joint pain. 

Platelet rich Plasma Injection Grafts for Musculoskeletal Injuries: A Review.  (2008)
This review of the medical literature explores the evidence to support the use of PRP Prolotherapy for musculoskeletal injuries.

Prolotherapy for Musculoskeletal Pain.  (2007)
This primer on Prolotherapy discusses how Prolotherapy helps with resolving musculoskeletal pain. 

Prolotherapy: Basic Science, Clinical Studies and Technique.  (2006)
This textbook chapter discusses the basic science of Prolotherapy, reviews the medical literature, and discusses the technique of Prolotherapy for joint and musculoskeletal pain.