Ankle Sprain or Tear
Platelet-Rich Plasma or Hyaluronate in the Management of Osteochrondral Lesions of the Talus. (2012)
Injection of platelet-rich plasma in ankle cartilage lesions resulted in a significantly better outcome than injection of hyaluronate, with decrease in pain scores and increase in function.
The Use of Platelet-Rich Plasma in the Management of Foot and Ankle Conditions. (2011)
This article discusses use of Platelet Rich Plasma and Bone Marrow Aspirate in 684 patients with lower extremity injuries and pain, and concludes that healing is more complete and rapid when used.
Platelet-Rich Plasma: More than a last resort? (2011)
This review article discusses the PRP controversy and concludes it appears to have great value in the healing of lower extremity injuries.
Dextrose Prolotherapy Injections for Chronic Ankle Pain. (2010)
In this observational study improvement was noted in patients treated for ankle pain with dextrose Prolotherapy, resulting in less pain, stiffness, increased range of motion, more activity and less need for medication.
High Resolution Ultrasound and Magnetic Resonance Imaging to Document Tissue Repair After Prolotherapy. (2006)
A Report of Three Cases (including Ankle). A near thickness tear of the Anterior Talofibular Ligament and Deltoid ligaments in the ankle are documented resolved with dextrose Prolotherapy. At patient follow up a year and a half later patient states "full speed" without weakness, pain or instability.